GEXSCOPE® Single Cell RNA Library Kit GEXSCOPE® Single Nucleus RNA Library Kit NEW! - GEXSCOPE® Microbial Single Cell RNA Library Kit HD (Yeast) GEXSCOPE® Single Cell V(D)J Kit DynaSCOPE™ Single Cell Dynamics RNA Library Kit FocuSCOPE™ Single Cell Targeted Capture Kit sCircle™ Single Cell Full-length TCR sequencing CLindex™ Sample Multiplexing Kit NEW! - sCelLiVE™ Tissue to Living Single Cell Suspension Kit NEW! - AccuraCode® RNA Library Construction Kit
GEXSCOPE® Single Cell V(D)J Kit enables simultaneous detection of T-cell or B-cell receptor gene expression, together with whole transcriptome expression at single-cell level.
GEXSCOPE® Single Cell V(D)J Kit utilizes specially designed probes on beads to capture all T-cell/B-cell receptor constant regions, to construct the V(D)J library. At the same time, poly-T on beads is utilised to capture all mRNA in the same cell, to construct the whole transcriptome library.
Based on the high RNA binding specificity introduced by targeted probes, GEXSCOPE® Single Cell V(D)J Kit can achieve high capturing efficiency during RNA molecule enrichment. GEXSCOPE® V(D)J library generates high BCR/TCR diversity, high V(D)J mapping rates, and high medium UMI/gene per cell.
GEXSCOPE® Single Cell V(D)J Kit can be used to analyze the composition, abundance and alterations of TCR/BCR molecules within a tissue at single-cell level. This can be applied for exploring tumor microenvironment, immune diseases, viral infection and infectious disease.